Abstract 17575: Carbon Monoxide Intoxication Induced Left Ventricular Dysfunction
Introduction: Carbon monoxide (CO) intoxication could cause significant cardiac injury. Cardiac dysfunction after CO intoxication can be presented as various clinical patterns. The echocardiographic findings after CO intoxication are poorly defined. The purpose of this study was to evaluate the clinical patterns of left ventricular (LV) dysfunction using echocardiography.
Methods: One-hundred thirty two CO intoxicated patients (81 males, 46 ± 20 year-old) with CO intoxication were enrolled. Clinical, demographic and laboratory data and transthoracic echocardiographic findings were analyzed.
Results: Left ventricular dysfunction developed in 29 patients (15 males, 47 ± 20 year-old). The LV dysfunction group showed higher lactate level (5.8 ± 3.3 vs. 4.1 ± 3.5 mmol/L, p=0.024) and lower base excess (-8.2 ± 6.0 vs. -4.8 ± 4.7 mEq/L, p=0.001) compared with normal LV function group. Among the LV dysfunction group, 3 different echocardiographic patterns were presented (Table). Regional wall motion abnormality (RWMA) was presented in 14 patients. Akinesia of the mid and apical segments of LV with sparing of the basal segments, typical finding of Takotsubo cardiomyopathy, was presented in 8 patients. Global hypokinesia of LV was presented in 7 patients.
Conclusions: Our results demonstrate that CO intoxication could induce various patterns of LV dysfunction.
Author Disclosures: J. Park: None. K. Seo: None. B. Choi: None. S. Choi: None. M. Yoon: None. G. Hwang: None. S. Tahk: None. J. Shin: None.
- © 2014 by American Heart Association, Inc.