Abstract 17318: Defining the Minimal Detectable Within-Person Change in Life’s Simple 7 (LS7) Scores
Introduction: In 2010, the AHA developed LS7 as a metric to define ideal cardiovascular (CV) health. LS7 is being used to track health over time. However, data on discriminating within-person change in LS7 scores over time from random variability are limited.
Hypothesis: We determined the minimal detectable within-person change in LS7 using data from the subset of Third National Health and Nutrition Examination Survey participants who completed two study examinations.
Methods: Each LS7 component (cigarette smoking, physical activity, diet, body mass index, blood pressure (BP), cholesterol and glucose) was determined during an interview or study visit and re-assessed at the second clinic examination conducted a median of 17 days later (range 3-48 days). We included 613 participants without a history of CV disease. Each LS7 component was assigned a score of 0 (ideal), 1 (intermediate) and 2 (poor) and these scores were summed to achieve an overall score ranging from 7 (better health) to 21 (worse health).
Results: For the overall population, the mean LS7 score was identical at each visit (13.5 SD+2.2). Overall, 54% of participants had no change in their LS7 score and 20%, 5% and <1% had a change of 1, 2 or ≥3 points, respectively (Figure). The within-person standard error of the mean for change in LS7 scores was 0.82, which equated to a within-person minimal detectable change of 2.27 points. Only 0.7% (4/613) of the participants had a change in LS7 scores ≥ 2.27 between examinations.
Conclusions: In conclusion, within-person changes on LS7 of >3 points over time may represent a real change in health.
Author Disclosures: M.M. Safford: Research Grant; Significant; Amgen Inc. Consultant/Advisory Board; Modest; Diadexus. M. Cushman: None. N.R. Redmond: None. G. Howard: None. P. Muntner: Research Grant; Significant; Amgen Inc. Consultant/Advisory Board; Modest; Amgen Inc.
- © 2014 by American Heart Association, Inc.