Abstract 17168: Factors Influencing Detection of Gadolinium Delayed Enhancement in Acute Myopericarditis
Objective: to correlate the presence of delayed enhancement (DE) in acute myopericarditis with clinical and echocardiographic and other cardiac MRI (CMR) findings.
Methods: Retrospective analysis of all patients admitted for acute myoperdicarditis and studied with CMR from 2007-2014. Epidemiological and laboratory data were registered, as well as cardiac imaging information from CMR and echocardiography. The optimum sensitivity and specificity of threshold values of Troponin- I (TnI) to predict DE were examined by ROC analysis. A logistic regression analysis predicted the presence of DE for different values of TnI.
Results: 49 episodes were included. Mean age was 31.8 (12.5) years and 75.5% were male. TnI was augmented in all cases and its mean value was 15.4 ng/mL (IQR 23-41). Mean length of in-hospital stay was 5.3 (3) days. Mean time until CMR was performed was 6.2 (6.6) days (the table). DE was detected in 63.3% of cases. According to the ROC analysis, a threshold value of TnI ≥ 7.48 ng/mL had a sensitivity of 84% and specificity of 66% to predict presence of DE (the figure). A regression analysis included age, LV mass, left atrial size and TnI but only TnI was an statistically significant factor to predict DE [OR = 1.14, CI 95%= (1.04-1.26), p= 0.006].
Conclusions: In patients admitted for acute myopericarditis with elevated TnI undergoing cardiac MRI, gadolinium delayed enhancement is present in 63.3% of cases. Most patients have preserved LVEF with no pericardial effusion. A threshold value of TnI ≥ 7.48 ng/mL predicts detection of delayed enhancement with a 85% likelihood.
Author Disclosures: M. Luaces: None. J. Florez: None. M. Erdociain: None. J. Perez: None. A. Bustos: None. A. de Agustin: None. L. Pérez de Isla: None. C. Macaya: None.
- © 2014 by American Heart Association, Inc.