Abstract 17011: Gender Differences in the Cardiovascular Risk Factors in First acute myocardial infarction in a Middle Eastern Country over a 20-year period
Introduction: Coronary artery disease (CAD) is a global health problem and a leading cause of death worldwide.
Hypothesis: In Middle East, the rate of CAD is expected to rise in parallel with the increase in per capita income and cardiovascular risk factors (CVRFs) burden. The present study evaluates temporal trends in CVRFs stratified by gender over a 20-year period in Qatar.
Methods: All patients hospitalized with first acute myocardial infarction (AMI) during the study period were analyzed and compared in 2 groups: group 1 (1991-2000) and group 2 (2001-2010).
Results: Among 10,915 patients who were admitted with first AMI, 9610 (88%) were men and 1305 (12%) were women. The overall mean age was 52.7±11.8 years. The overall rate of
hospitalization increased from 34% to 66% (p<0.001), representing a relative increase by 48%.The proportion of men to women remained relatively constant.During the study period. most of the measured CVRFs have shown a steady upward trend in both sexes. Compared to men, women were older, had a higher burden of CVRFs and presented mainly with non-ST-elevation MI. However, in comparison to group 1, women in group 2 had significant increases in the prevalence of dyslipidemia and obesity. Multivariate logistic regression analysis showed that female gender was independent predictor of in-hospital mortality (odd ratio 1.92, 95% CI 1.60-2.77).
Conclusions: Over the study period, the rate hospitalization increased by nearly half, this potentially could be explained by the unfavorable alteration in the major modifiable CVRFs. Furthermore, women with acute myocardial infarction represent a higher risk group.
Author Disclosures: E. Ahmed: None. A. El-Menyar: None. J. Al Suwaidi: None. H. AlBinAli: None. R. Singh: None. A. Gehani: None.
- © 2014 by American Heart Association, Inc.