Abstract 16938: Relationship of Healthy Diet with Components of Blood Pressure: a Study from the Hispanic Community Health Study/Study of Latinos
Background: The Alternative Healthy Eating Index (AHEI-2010) is a measure of adherence to U.S. dietary guidelines and is inversely related to cardiovascular and diabetes risk. It is unknown if the AHEI-2010 is associated with distinct blood pressure (BP) components including measures of pulsatile versus steady state load (surrogates of large and small artery disease).
Methods: We studied 12,445 participants from 4 U.S. sites in the Hispanic Community Health Study / Study of Latinos who provided at least one 24h dietary recall, were free of cardiovascular disease, and not on anti-hypertensive medications. We used weighted linear regression for complex survey sampling and non-parametric spline models to examine the cross-sectional relation of AHEI-2010 with components of BP (systolic BP [SBP], diastolic BP [DBP], pulse pressure [PP], mean arterial pressure [MAP]) while adjusting for established clinical correlates of BP.
Results: The target population mean age was 38 years (0.22 s.e.) with 52% women, 21% smokers, and 10% with untreated hypertension. The mean AHEI-2010 score was 47 (s.e. 0.18) and similar by sex. Mean AHEI-2010 increased with age from 43 (s.e. 0.24) in 18-29 year olds to 52 (s.e. 0.46) in 70-74 year olds. In multivariable-adjusted analyses, the AHEI-2010 was inversely associated with all BP components (P<0.01 for all) (Figure). In particular, each 10 point increase in AHEI-2010 was associated with a decrease in pulse pressure of 1 mmHg (P=0.0001).
Conclusion: In a large cohort of Hispanic/Latino adults, healthier diet as reflected by a higher AHEI-2010 is inversely related to all BP components including measures of pulsatile load (representing large artery disease) and steady state load (representing small artery disease). Because the AHEI-2010 emphasizes high intakes of fruit, vegetables, and whole grains and low intake of sodium, its association with lower BP components could reflect pathways by which diet influences cardiovascular health.
Author Disclosures: N.A. Bello: None. B. Claggett: None. F. Rodriguez: None. J. Cai: None. A. Moncrieft: None. K. Garcia: None. M. Del Rios Rivera: None. R.C. Kaplan: None. M.L. Daviglus: None. S.D. Solomon: None. S. Cheng: None.
- © 2014 by American Heart Association, Inc.