Abstract 16319: Distribution and Severity of Myocardial Ischemia Modify Mitral Regurgitation (MR) Response to Percutaneous Coronary Intervention (PCI)
INTRODUCTION: Myocardial properties impact mitral valve closure, but MR response to PCI is poorly understood. This study tested if PCI alone can improve MR and whether MR change is predicted by myocardial ischemia pattern.
METHODS: The population comprised consecutive patients with perfusion evidenced ischemia and no intrinsic mitral valve disease undergoing echocardiography (echo) and PCI. Stress SPECT myocardial perfusion imaging (MPI) was used to measure rest perfusion and inducible ischemia via a 17 segment model, 5 point per segment scoring system. Echo (within 1 week of MPI) measured MR and LV chamber dimensions; followup echo (≥1 month post PCI) assessed change in MR.
RESULTS: 358 patients undergoing PCI (50% LAD
Author Disclosures: P. Goyal: None. S.C. Volo: None. A. Feher: None. M.M. Petashnick: None. S. Gurevich: None. J.D. Kochav: None. P. Kampaktsis: None. R.M. Levine: None. M. Ratcliffe: None. F.J. Wong: None. L.N. Girardi: None. R.B. Devereux: None. J.W. Weinsaft: None.
- © 2014 by American Heart Association, Inc.