Abstract 15790: Simultaneous Longitudinal Strain in All 4 Cardiac Chambers - A Novel Method to Assess Cardiac Function
Introduction: Simultaneous assessment of longitudinal strain (LS) by 2D speckle tracking echocardiography (STE) in all 4 cardiac chambers could potentially provide a yet untapped venue for the assessment of chamber mechanics. Our goal was to study LS curves obtained simultaneously from all 4 cardiac chambers in normal subjects categorized by age and gender, in order to gain insight into the functional relationships between chambers.
Methods: We studied 109 normal subjects (58 men, 51 women; age 39±13) in whom it was possible to obtain apical 4-chamber views that contained the entire left and right ventricles (LV, RV) and both atria (LA, RA) in the same sector. 2D STE was performed in all 4 chambers in the same cardiac cycle to measure LS using vendor-independent software (Epsilon Imaging) (figure 1A). The inter-ventricular septum was considered part of the LV, while RV strain was measured only in the free-wall segments. The inter-atrial septum was included in the LS measurements of both atria.
Results: Strain curves of the RV and RA were larger in magnitude than the corresponding left heart chambers (figure 1B), resulting in larger peak systolic LS values (table, bottom left).LS for the LA peaked significantly later than the LV, RV and RA. Gender differences were found only in the LV and LA, where peak systolic LS values were significantly larger in magnitude in females than males (table, bottom left). Age differences were significant only in the LA, where the younger age groups (<40) showed larger magnitude strain values than the older group (≥60) (table, top right, stars).
Conclusions: Simultaneous measurement of LS provides new insight into inter-chamber relationships including age and gender differences in normal subjects. This new tool may prove useful in evaluating diseases that affect cardiac chambers differently.
Author Disclosures: K. Addetia: None. M. Takeuchi: None. F. Maffessanti: None. L. Weinert: None. J. Hamilton: None. V. Mor-Avi: None. R.M. Lang: None.
- © 2014 by American Heart Association, Inc.