Abstract 14963: The Accessory Papillary Muscles and Papillary Muscle Hypertrophy are Associated with Sudden Cardiac Arrest of Unknown Cause
Introduction: The cause of sudden cardiac arrest (SCA) in a considerable number of patients remains unknown. The present study was performed for elucidating the associations between the morphology of the papillary muscles and SCA.
Hypothesis: The morphology of the papillary muscles should be associated with SCA.
Methods: We retrospectively included 190 patients with SCA. History, laboratory data, ECG, echocardiography, coronary angiography, and cardiac CT/MRI were analyzed for elucidation of causes of SCA. We compared incidence of the accessory papillary muscles between the patients with SCA of unknown cause (including idiopathic ventricular fibrillation) and the patients with SCA of known causes. We also compared incidence of the accessory papillary muscles between the patients with SCA of unknown cause and age- and sex-matched 2-fold patients without SCA. The accessory papillary muscles were defined as the papillary muscles with origins separated from the anterolateral and posteromedial papillary muscles.
Results: The patients with SCA of unknown cause and the patients with known causes were 49 patients (age, 49.9 ± 15.9 years; male, 38) and 141 patients (age, 54.2 ± 16.6 years; male, 121). The known causes of SCA were coronary artery diseases, channelopathies, and cardiomyopathies in order of frequency. The incidence of the accessory papillary muscles in the patients with SCA of unknown cause was significantly higher than the patients with SCA of known cause (24.5% and 7.8%, respectively; p = 0.002) or the patients without SCA (7.1%, p = 0.003).
Conclusions: It suggests that the accessory papillary muscles are associated with sudden cardiac arrest of unknown cause.
Author Disclosures: J. Uhm: None. H. Lee: None. T. Kim: None. N. Kim: None. J. Park: None. J. Youn: None. B. Joung: None. H. Pak: None. M. Lee: None.
- © 2014 by American Heart Association, Inc.