Abstract 14710: Ideal Cardiovascular Health in Younger Age and Functional Disability in Older Age -- The Chicago Heart Association Detection Project in Industry (CHA) 32 Year Follow-up Health Survey
Background: Ideal levels of all major cardiovascular disease (CVD) risk factors (RF), i.e., low risk (LR), in younger age are associated with lower subsequent CVD morbidity and mortality in older age. However, data are limited on the relationships of LR profile in younger age with functional disability in older age.
Methods: We used data from 3,669 men and 2,345 women from the CHA Study, ages 29-68 in 1967-73, free from major ECG abnormalities, history of diabetes, or MI at baseline with functional disability data from the 2003 health survey. Functional disability was categorized as having: 1)any disabilities in activities of daily living (ADL), 2)any disabilities in instrumental ADL(IADL) but no ADL, or 3) no disability. LR status [i.e., SBP/DBP (≤120/≤80 mmHg and no antihypertensive medication), serum total cholesterol (<200 mg/dl and no cholesterol-lowering medication), not smoking, BMI < 25 kg/m2, and no diabetes0] was assessed at baseline. Details on definitions of ADL/IADL disabilities and RF status are shown in Table footnote.
Results: Only 6% of participants were LR at baseline; follow-up mean age was 76.6 years, 11% of the cohort reported having IADL disabilities, and 7% having ADL disabilities. With multivariate-adjustment (see Table), baseline LR was associated with the lowest likelihood of having any ADL or IADL disabilities 32 years later (P-trends < 0.001). Compared to those with ≥2 RFs, the odds of having any ADL disabilities vs. no disability in persons with baseline LR, 0 RF, and 1RF were lower by 60%, 50%, and 40%, respectively. Similar results were observed for having any IADL disabilities.
Conclusion: Having an ideal CVD RF profile at younger age is associated with lowest functional disabilities in older age and thus can reduce the loss of independence and improve quality of life in older adults.
Author Disclosures: T.T. Vu: None. K. Liu: None. D.M. Lloyd-Jones: None. D.B. Garside: None. M.L. Daviglus: None.
- © 2014 by American Heart Association, Inc.