Abstract 14696: Association of Air Pollution With Increased Incidence of Ventricular Tachyarrhythmias Recorded by Implantable Cardioverter Defibrillators
Introduction: Probability of relationship between arrhythmia and air pollution was recently reported.
Hypothesis: This study investigated the acute effects of exposure to air pollutions on the ventricular tachyarrhythmias (VT) in an East Asian country, where was usually affected by yellow sand phenomenon.
Methods: We used implanted cardioverter defibrillator (ICD) records of VT to assess the role of air pollution as a trigger of these potentially life-threatening events. The study cohort consisted of 126 cardiac patients with ICD devices in the Seoul metropolitan area who were followed for an average of 5.1±3.3 years between Nov 1999 and Jan 2014. Fine particle mass and gaseous air pollution plus temperature and relative humidity were measured on almost all days, and black carbon, sulfate, and particle number on a subset of days.
Results: During the study period, 141 incident VTs were observed. The trend of association was observed between VT and air pollution such as PM10, O3, NO2, and CO. We found statistically significant association between sulfur dioxide (SO2) and overall VT events (p=0.028). For SO2, increased odds were found immediately (OR 1.26, 95% CI 1.04 - 1.53, p=0.018), and within 2 hour (OR 1.25, 95% CI 1.04 - 1.51, p=0.018) and 6 hour (OR 1.22, 95% CI 1.02 - 1.46, p=0.028) after the exposure of air pollution. In subgroup analysis, the association with SO2 was found in nonsustained VT (OR=1.28, 95% CI 1.01 - 1.60, p=0.038).
Conclusions: The association between air pollution and VT recorded by ICD was observed in East Asian country. Especially, the exposure to SO2 is significantly associated with the onset of VT.
Author Disclosures: I. Kim: None. J. Sohn: None. S. Lee: None. H. Pak: None. M. Lee: None. C. Kim: None. B. Joung: None.
- © 2014 by American Heart Association, Inc.