Abstract 13994: Masked Hypertension in Ischemic Stroke Patients
Background: Masked hypertension (MHT) is characterized by normal clinic blood pressure (BP), but elevated ambulatory BP (ABP) and associated with increased risk for target organ damage. We assessed clinical and metabolic characteristics of MHT in ischemic stroke patients.
Methods: Clinic and ABP was recorded in 219 patients (aged 15-60 years) included in the prospective Norwegian Stroke in the Young Study (NORSYS) 3 ± 1 month after the acute stroke to identify normotension (NT), white-coat hypertension (WCHT), MHT and sustained hypertension (HT).
Results: MHT was found in 10% of patients. In univariate analyses, patients with MHT had higher systolic ABP and serum triglycerides than those with HT, higher body mass index and waist circumference than those with NT and WTCH and lower serum HDL cholesterol than all other BP categories (all p<0.01) (Table). In multivariate logistic regression analysis, lower HDL cholesterol (OR 7.14[95% CI 1.61-33.33], p<0.01), lower fasting blood glucose (OR 2.44[95% CI 1.15-5.26], p<0.05) and higher systolic ABP (OR 1.07[95% CI 1.03-1.11], p<0.01), were independently associated with MHT. Adding obesity, waist circumference, alcohol consumption or fasting serum triglycerides to the model did not change the results.
Conclusion: In young and middle-aged ischemic stroke patients in the NORSYS registry, combined lower HDL-cholesterol and absence of diabetes were particularly associated with presence of masked HT.
Author Disclosures: S. Saeed: None. U. Waje-Andreassen: None. A. Fromm: None. H. øygarden: None. E. Gerdts: None.
- © 2014 by American Heart Association, Inc.