Letter by Ma et al Regarding Article, “Ischemic Postconditioning During Primary Percutaneous Coronary Intervention: The Effects of Postconditioning on Myocardial Reperfusion in Patients With ST-Segment Elevation Myocardial Infarction (POST) Randomized Trial”
To the Editor:
We read with great interest the article by Hahn et al1 that was published recently in Circulation. The authors conducted a large-scale study to demonstrate cardioprotective effect by ischemic postconditioning at the target lesion in patients with ST-segment–elevation myocardial infarction undergoing percutaneous coronary intervention. However, postconditioning failed to improve myocardial reperfusion in patients with ST-segment–elevation myocardial infarction undergoing primary percutaneous coronary intervention with standard practice.
Postconditioning is still in early stages of development, and clinical implications remain to be established as stated …