Letter by Laskey Regarding Article, “Systemic Hypertension in Low-Gradient Severe Aortic Stenosis With Preserved Ejection Fraction”
To the Editor:
I read with great interest the recent study by Eleid et al1 on the topic of systemic arterial hypertension in patients with low-gradient severe aortic stenosis and preserved ejection fraction. The concept that alterations in systemic arterial hemodynamics may have unique and unexpected consequences for patients with aortic valve stenosis is particularly important given the current emphasis on the recognition and treatment of aortic valve stenosis.
Eleid et al have nicely shown that afterload reduction with nitroprusside in patients with aortic valve stenosis, low gradients (at rest), and severe systemic arterial hypertension not only results in the reduction in intracardiac filling pressures (in patients with …