Abstract P053: Body mass index is a predictor for developing hypertension among the younger Japanese elderly: Findings from the New Integrated Suburban Seniority Investigation project
Background: Obesity has been associated with hypertension. However, few prospective cohort studies have focused on younger elderly people.
Objective: This study aimed to determine whether body mass index (BMI) was associated with the development of hypertension in younger Japanese elderly from the New Integrated Suburban Seniority Investigation project (NISSIN) project age-specific cohort study.
Methods: A total of 1,694 (767 males and 927 females) approaching the age of 65 years and without hypertension (systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or undergoing treatment) at baseline (1996-2005) were enrolled. Baseline characteristics of the study participants were obtained from health check-ups and self-administered questionnaires. Development of hypertension was determined during secondary health check-ups at the same site when the participants reached 70 years of age. To obtain multivariate-adjusted odds ratios (ORs) for development of hypertension in relation to baseline BMI, we controlled for possible confounders including survey year, smoking, alcohol consumption, regular exercise, hypercholesterolemia and hyperglycemia at baseline, history of myocardial infarction, and family history of hypertension.
Results: After eliminating participants who did not participate in the second health check-ups, data from 1,016 (468 males and 548 females) participants were analyzed. At the age of 70 years, 122 (59 males and 63 females) participants had developed hypertension. Using fully adjusted models, compared to participants with a BMI of 18.5 to 22.9, ORs of male participants with a BMI of 23.0 to 24.9 and ≥25.0 were 2.87 (95% CI, 1.40-5.90) and 3.20 (95% CI, 1.48-4.90), respectively. For females with a BMI of 23.0 to 24.9 and ≥25.0, they were 1.06 (95% CI, 0.54-2.11) and 1.84 (95% CI, 0.86-3.93), respectively.
Conclusions: There was a significant relationship between BMI and development of hypertension among younger Japanese elderly men. Our findings suggest that weight management may be beneficial in the prevention of hypertension, even in the younger elderly.
Author Disclosures: S. Ukawa: None. A. Tamakoshi: None. K. Tsushita: None. K. Wakai: None. M. Ando: None. H. Ohira: None. S. Okabayashi: None. M. Matsushita: None. W. Zhao: None. J. Oikawa: None. T. Kawamura: None.
- © 2014 by American Heart Association, Inc.