Letter by Eberlein and Reed Regarding Article, “Transplantation for Idiopathic Pulmonary Arterial Hypertension: Improvement in the Lung Allocation Score Era”
To the Editor:
We read with great interest the article by Schaffer et al1 on transplantation for idiopathic pulmonary arterial hypertension (IPAH). A conclusion of the authors is that donor-to-recipient sex matching is associated with better survival. Furthermore, sex matching as a priority for IPAH patients with less acute disease is recommended. The accompanying editorial emphasizes that the findings regarding sex matching need to be evaluated in more detail.
An important detail unaccounted for by Schaffer et al1 is that sex is a major determinant of lung size.2 Lung size can be estimated by calculating the predicted total lung capacity (pTLC) from …