Abstract 9535: Image-Based Validation of Left Ventricular Mass and Stroke Volume in Fetal Sized Hearts Using 4D Nongated Echocardiography
Background: The non-gated 4D echocardiogram is the most recently developed tool for visualizing cardiac mechanics without the requisite use of electrocardiogram (EKG) wires. This study was designed to determine the left ventricular (LV) stroke volume (SV) and mass (LVM) of fetal heart models using non-gated 4D echo.
Methods: 4D volumes of fetal heart models (rabbit LVs) were acquired at five different stroke volumes (SV) between 1 and 5mL with an X6-1 matrix transducer interfaced with a Philips® iU22 ultrasound system. Data was collected at two different stroke rates (SR), 40 and 80 strokes per minute, for each SV and analyzed offline with QLab®. LVM and SV were calculated in QLab® according to stacked endocardial and epicardial ellipses and compared to displacement data.
Results: We found no significant difference between the displacement and 4D echo-derived values for LVM (R2=0.98, p<0.01) and SV (R2=0.92, p<0.01). It was also determined that 97% of the data was contained within a 95% confidence interval (CI) in a Bland-Altman analysis.
Conclusions: Thus, we determined that the new Philips® iU22 4D echocardiogram is an accurate way to measure the LV mass and SV of fetal hearts.
- © 2013 by American Heart Association, Inc.