Abstract 71: Comparison of Outcome of Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital and In-Hospital Cardiac Arrest
Objectives: The aim of this study was to investigate the effects of extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) and compare the results with those of in-hospital cardiac arrest (IHCA).
Background: ECPR, considered an adjuvant therapy for IHCA, has been previously applied for OHCA with unsatisfactory results.
Methods: We reviewed our prospectively collected extracorporeal membrane oxygenation (ECMO) results and analyzed the data for patients who received ECPR for OHCA or IHCA in the last 5 years. Pre-arrest, resuscitation, and post-resuscitative data were evaluated.
Results: In the last 5 years, ECPR was used 230 times for OHCA (n=31) and IHCA (n=199). The basic demographic data showed significant differences in age, cardiomyopathy, and location of the initial CPR. Duration of ischemia was shorter in the IHCA group (44.4 ± 24.7 min vs. 67.5 ± 30.6 min, p 0.05). Survival was acceptable (about 33%) in both groups when the duration of ischemia was no longer than 75 minutes.
Conclusions: In addition to having a beneficial effect in IHCA, ECPR can result in an acceptable survival and neurological outcome in selected OHCA patients after prolonged cardiopulmonary resuscitation. Our results suggest that further investigation of the use of ECMO in OHCA is warranted and that ECMO may be an effective adjuvant therapy.
- © 2013 by American Heart Association, Inc.