Research Priorities for In-Hospital Cardiac Arrest: An Agenda for the Next Decade
There are an estimated 200,000 to 300,000 cardiac arrests which occur annually in U.S. hospitals, with relatively low survival rates. In-hospital cardiac arrest (IHCA) remains a ‘silent epidemic’, and as many patients die of IHCA each year in the U.S. as lung cancer. Until recently, however, little was known about the epidemiology, processes of care, and outcomes of IHCA.
In the past decade, a number of key studies have provided important insights. We now know that certain process of care factors, such as defibrillation time and duration of resuscitations, are tightly linked to patient survival and neurological outcomes. Several studies have also demonstrated substantial hospital variation in processes of care and survival, suggesting that some hospitals are able to excel in the treatment of IHCA. In fact, survival after IHCA has improved markedly over the past decade (14% in 2000 to 22% in 2009), but these gains have been uneven across sites. Nonetheless, the factors which distinguish top-performer hospitals in IHCA survival from other hospitals have yet to be defined.
In this lecture, Dr. Chan will review the seminal epidemiological and outcomes studies on IHCA over the past decade. He will then propose a research agenda for IHCA for the next decade, as well as promote a paradigm shift in the conceptual model of IHCA, investigator collaborations, and research methodologies.
- © 2013 by American Heart Association, Inc.