Abstract 333: Simple Conventional Cooling Methods Without Temperature Feedback Regulation Are Not Inferior to Automatic Cooling Device for Improvement of Neurologic Outcome of Cardiac Arrest Patients
Objective: We assessed the hypothesis that therapeutic hypothermia (TH) implemented by only conventional uncontrolled cooling method is not associated with worse neurologic outcome compared to the cooling device equipped with temperature feedback control, regardless of surface or endovascular cooling.
Methods: We performed a multicenter retrospective registry-based study of adult out of cardiac arrest patients treated with TH presenting to 24 hospitals across South Korea during the period from January 2007 to December 2012. Patients who received TH only by conventional methods such as ice packs, cold fluids, and other convective methods were assigned to one group, and those who received TH by automatic device using body wraps, hydrogel pads and endovascular cooling catheter were assigned to another. Choice of method was based upon device availability of the relevant hospital.
Results: Of a total of 930 OHCA patients entered in the registry, 851 were included in the analysis, of which 58 underwent only conventional cooling and remaining 793 underwent temperature feedback controlled cooling. More adverse events such as overcooling or rebound hypothermia occurred in the conventional method group, which was significantly associated with poor neurological outcome (cerebral performance category 3-5) at hospital discharge. In multivariate logistic regression analysis, conventional cooling method group was not associated with worse neurologic outcome compared to the automatic cooling device.
Conclusions: In our study, conventional cooling method without automatic temperature feedback control was not associated with poor neurological outcome at hospital discharge, although it is associated with more adverse events.
- © 2013 by American Heart Association, Inc.