Abstract 315: Characterization of Out of Hospital Resuscitation Utilizing Blood Transfusion
Introduction: While blood transfusion in the hospital setting has been extensively studied, little data exists on out of hospital administration of blood products. We aimed to characterize patients receiving out of hospital blood product transfusion in a critical care transport network that carries blood products.
Methods: We performed a retrospective review of patients transported by a regional critical care transport service from 1/1/2003 to 6/30/2012 who received blood products during transport. This service carries two units of un-crossmatched Packed Red Blood Cells (pRBCs) on every transport. We describe prehospital factors (vital signs, mechanism of injury, volume and type of blood product transfused) associated with blood transfusion. We further categorized out of hospital transfusions of blood products into three groups based on the volume transfused (lt350 ml, 350-700ml, gt700ml). We compared in-hospital outcomes (mortality, volume and type of subsequent blood transfusion, and need for emergent surgery [lt24 hours]) among these three groups to ascertain the impact of prehospital blood product transfusion.
Results: We reviewed 1441 transports in which blood products were transfused. Most transfusions were inter-facility transfers (92%, CI 91-93%) and for non-traumatic illness (75%, CI 73-77%). The most common reason for transport was upper gastrointestinal bleeding (20%, 18-22%). A vast majority, 80% (CI 78-82%), of patients required subsequent in-hospital blood transfusion. In hospital 30-day mortality was high, 22% (CI 20-25%), as was need for emergent surgery 27% (CI 25-29%). Mean length of stay was 10.6 days and mean ICU length of stay was 7.2 days. Among those receiving blood products, those transfused with >700ml had higher heart rates (94 vs. 103, p=0.01), whole blood lactate levels (3.5 vs. 6.2, p<0.01), and lower systolic blood pressure (108 vs.122, p<0.01)
Conclusions: In this sample, the majority of patients receiving blood during critical care transport are during inter-facility transports and for non-traumatic conditions. Gastrointestinal hemorrhage is the most common indication for transfusion and 30-day mortality in this cohort is high.
- © 2013 by American Heart Association, Inc.