Abstract 242: Association Between Charlson Comborbidity Illness Components and Outcome Following Cardiac Arrest
Introduction: The independent effect of pre-arrest comorbid illness on survival and good neurologic outcome following resuscitation from cardiac arrest has not been defined.
Methods: Convenience sample of patients treated at a post-cardiac arrest center between 1/1/2005 and 7/22/2009 with Charlson Comborbidity Index (CCI) scores determined. We obtained information and injury severity based on Pittsburgh Cardiac Arrest Category (PCAC) were determined from the medical records. Univariate logistic regression was used to determine the association between individual CCI components and survival and good neurologic outcome (defined as discharge home or to acute facility) were primary outcomes. A multivariate model including PCAC, shockable rhythm, and CCI components found significant in the univariate model was generated. Goodness of fit was evaluated using the Hosmer Lemeshow value.
Results: Of 348 subjects, the majority (56%) were male, experienced OHCA (54%), with a mean age of 61 (±16) years. VF/VT was the most common rhythm (39%), 32% received coronary angiography, the majority (66%) were comatose, and 56% received hypothermia. VF/VT was associated with survival in the multivariate model whereas PCAC and age was associated with non-survival. VF/VT, cardiac catheterization, and history of myocardial infarction were associated with good outcome in the multivariate model, whereas PCAC was associated with poor outcome. (Table)
Conclusions: Prior history of diabetes and more severe injury severity associate with worse outcomes whereas factors associated with cardiac etiology arrests (MI, VF/VT, catheterization) are associated with improved outcomes.
- © 2013 by American Heart Association, Inc.