Abstract 18565: Trends and Outcomes in the Use of Extracorporeal Membrane Oxygenation for Adults in the United States: A 10 year survey
Introduction: Extracorporeal membrane oxygenation (ECMO) has been used in hospitalized patients with severe cardiac and respiratory failure. However, little is known about trends in ECMO utilization and survival, particularly in adults.
Methods: We evaluated the use of ECMO in the United States between 2001 to 2009 using the Nationwide Inpatient Sample (NIS) database. National estimates were measured using sampling weights of NIS. We excluded children and those patients who underwent ECMO during open-heart surgery.
Results: National estimates of ECMO use in the United States increased from 165 patients in 2000 to 1450 patients in 2009. The incidence rate was significantly increased from 5.4 patients per million to 44.3 per million (p <0.0001). Despite 9-fold increase in use of ECMO in ten years, the mortality rate remained high and did not significantly change (p=0.5) (Figure). ECMO use in the elderly (>65) accounted for one quarter of hospitalizations, and did not change in frequency over last 10 years (p<0.15).
Conclusions: This is the largest study of ECMO utilization in adults. Over ten years, despite widespread increase in use of this technology, there was no significant change in mortality rate and mortality remains high. Further studies will need to identify those patients most likely to benefit from ECMO
- © 2013 by American Heart Association, Inc.