Abstract 17048: The Value of the CHA2DS2-VASc Score for Refining Mortality and Stroke Risk Stratification in Diabetic Patients After Complete Revascularization Undergoing PCI
Diabetes is the important predictor of cardiovascular events. Limited data exist regarding evaluation of multiple risk factors for outcomes in diabetic patients with severe coronary artery disease (CAD). We aimed to assess the value of the CHA2DS2-VASc score as future predictive value for mortality and stroke in diabetic patients after complete revascularization undergoing PCI.
Methods: A cohort of consecutive diabetic patients with complete revascularization undergoing PCI was enrolled. In 592 diabetic patients with multi-vessel CAD undergoing PCI, we calculated CHA2DS2-VASc scores. The primary outcome was total mortality and stroke over a mean follow-up of 7.3 ± 2.6 years. We divided into 3 groups according to CHA2DS2-VASc score, CHA2DS2-VASc low score=2, 3 (243 (41.1%)), intermediate score=4, 5 (283 (47.8%)), and high score>=6 (66 (11.1%)).
Results: Patients with high CHA2DS2-VASc scores had a higher rate of mortality and stroke (log rank p=0.035) than those with low and intermediate CHA2DS2-VASc scores. Furthermore, compared with patients with low CHA2DS2-VASc, those with high CHA2DS2-VASc scores had an increased hazard ratio of mortality and stroke (HR 2.99, 95% CI 1.14-7.64, p=0.027) and hazard ratio of stroke was also higher in patients with high CHA2DS2-VASc scores than those with low CHA2DS2-VASc scores (HR 6.00, 95% CI 1.71-21.3, p=0.0058).
Conclusion: The CHA2DS2-VASc score provides critical information on risk of mortality and stroke in diabetic patients after complete revascularization undergoing PCI .
- © 2013 by American Heart Association, Inc.