Abstract 16258: Anxiety, Depression and Age: Implications for Women With Heart Failure
Anxiety and depression are common in patients with HF. Both are associated with poor outcomes in HF, including high morbidity and healthcare resource use. In women with HF, the relationship of anxiety and depression to age has not been examined. Our purpose was to identify correlates of persistent anxiety and persistent depressive symptoms in women with HF and determine if they differed by age.
Methods: We examined records of 344 women with HF (mean age 65 ± 13 years, and divided them into two groups based on age 55 as a cut point; 72 (21%) were ≤ age 55 years. Anxiety and depressive symptoms were measured with the Brief Symptom Inventory (BSI) and either the Beck Depression Inventory II (BDI) or the Patient Health Questionnaire 9 (PHQ-9). Scores were dichotomized at accepted cut-offs (BSI > .35; BDI > 15; PHQ-9 > 8) and were considered persistent if they lasted at least 3 months. To examine demographic, clinical, and psychological characteristics by age, bivariate analyses were conducted with Chi-square and t-test. Those significant at p ≤ .10 were included by simple forced entry in a multivariate logistic regression. Significance was set at < .05.
Results: In younger women, 52.8% and 17.3% experienced persistent anxiety and depressive symptoms, respectively, compared to 26.5% (p< .001) and 9.6% (p = .03) of older women. In multivariate analysis, younger age was associated with higher BMI, non-minority ethnicity, and persistent anxiety. Younger women were 3.2 times more likely to experience persistent anxiety, even when depressive symptoms were considered (Table).
Conclusions: Younger age is associated with persistent anxiety, but not persistent depressive symptoms, in women with HF. For these women, clinicians should incorporate regular screening for anxiety into their care and should re-evaluate symptoms regularly. In younger women with HF, future studies should test the effect of anti-anxiety interventions on clinical outcomes, including healthcare resource use.
- © 2013 by American Heart Association, Inc.