Abstract 16191: Incidence, Characteristics and Outcome of Sudden Cardiac Death During Sports in Women
Background: No specific data are available on sudden cardiac death (SCD) during sport activities among women in the general population.
Hypothesis: There are significant differences in SCD during sports in women compared to men.
Methods and results: From a prospective 5-year national survey, involving 820 subjects aged 10-75 years who presented with SCD (resuscitated or not) during competitive or recreational sport activities, 43 (5.2%) such events occurred in women, principally during jogging, cycling and swimming. The level of activity at the time of SCD was moderate to vigorous in 83.3% of these cases. The mean overall incidence of sports-related SCD was estimated between 0.59 (95%CI 0.39 to 0.79) and 2.17 (95%CI 1.38 to 2.96) per year per million of women sports participants, with no significant change with increasing age. Compared to men, the incidence of SCD in women was dramatically lower, particularly in the 45-54 year range (relative risk 0.033, 95%CI 0.015 to 0.075). Despite very similar circumstances (setting, presence of witnesses, cardiopulmonary resuscitation initiation, delay of intervention), survival at hospital admission (46.6%, 95%CI 31.0 to 60.0) was significantly higher than for men (odd ratio 2.03, 95%CI 1.09 to 3.77, P=0.02), with a similar rate of favorable neurological outcomes (80%). Cause-of-death appeared less likely to be associated with structural heart disease in women, compared to men (58.3% vs. 95.8%, P=0.0003).
Conclusions: Sports-related SCD in women participants appears dramatically less common (up to 30-fold less frequent), after adjusting for participation rates, compared to men. This should be considered in the future, to optimize pre-participation screening programs in the general population.
- © 2013 by American Heart Association, Inc.