Abstract 15511: Age Adjusted Health-Related Quality of Life in an ACHD Cohort
Objective: Studies measuring health related quality of life (HRQOL) with SF-36v2 in adult congenital heart disease (ACHD) patients have shown results similar to or worse than the general population. Average patient age, however, is less than the general population. We evaluated age-adjusted SF-36v2 HRQOL scores for ACHD patients.
Methods: We recruited 309 ACHD
patients: age 37y (18-80y); female 52%; white 93%; NYHA Class I/II >90%; insured 98%. Conditions were atrial septal defect (ASD) (n=34); coarctation (COA) (n=25); Fontan (n=68); d-transposition (n=41); tetralogy of Fallot (n=141). Subjects provided demographic data and completed the SF-36v2. SF-36v2 results include norm-based physical (PCS) and mental health (MCS) summary scores, with a score difference of > 3 points considered clinically important.
Results: Figures 1 and 2 show mean age-adjusted differences and 95% CI in PCS and MCS for each condition. Means differed across conditions (p<0.005), but PCS were normal for all conditions except ASD (p=.002) and COA (p=.02). Mean MCS exceeded normal for all conditions (p<.001) and did not differ across conditions (p=0.8).
Among patients, 50% had age-adjusted PCS scores and 76% MCS > 3 points above the population mean; 25% had PCS and 16% MCS > 3 points below.
Conclusions: Subjects showed remarkable normalcy in age-adjusted PCS and MCS despite severe ACHD conditions. These results are unexpected given reported medical and psychosocial issues in ACHD patients and they may not be generalizable.
The strong perceived health status reported may indicate differences in applying SF-36v2 to patients with a lifelong medical condition.
- © 2013 by American Heart Association, Inc.