Abstract 15313: The Association Between Diet Quality and Mortality in Incident Type 2 Diabetic Women
Background: Although many short-term follow-up clinical trials examined the impact of diet among type 2 diabetic patients on intermediate cardiovascular outcomes, the effect of post-diabetic diet on mortality among type 2 diabetic patients is unknown. We examined whether healthy diet with high alternative Health Eating Index (aHEI) is associated with mortality among incident type 2 diabetic women using long-term prospective cohort study.
Methods: Incident type 2 diabetic women (n=7305, mean age of diabetes diagnosis: 60.7 years old) from Nurses’ Health Study with no baseline cancer and cardiovascular disease were enrolled. Cox regression model was used to assess the multivariate association between aHEI and all-cause mortality, cardiovascular mortality and cancer mortality.
Results: A total 1668 deaths including 540 cardiovascular deaths and 381 cancer deaths were identified during 64219.5 person-years (28 years maximum follow up). The relative risk of all-cause and cardiovascular- related mortality in the highest aHEI quintile was 45% (RR: 0.55, 95% CI 0.46-0.66, p for trend < 0.0001) and 54% (RR 0.46 95% CI 0.33-0.64, p for trend < 0.0001) lower than the lowest quintile, respectively. The relative risk of cancer-related mortality in the highest aHEI quintile was 0.75(95% CI 0.52-1.08, p for trend 0.03).
Conclusions: There was an inverse association between adherence to healthy dietary habit and all-cause, and cardiovascular-related mortality among incident type 2 diabetic women.
- © 2013 by American Heart Association, Inc.