Abstract 15194: Achievement of TIMI-3-Flow Results in Significant Decrease in Hospital Mortality of Primary PCI for STEMI and PCI for NSTE-ACS - Findings of the Euro Heart Survey PCI-Registry
Background: Acute reperfusion is common in ACS within Europe. High success rates of reperfusion have resulted in improvement of hospital outcome. Little is known about the impact of non-reperfusion in PCI in clinical practice.
Methods: Between 2005 and 2008, 47,407 consecutive patients undergoing PCI were enrolled into the PCI-Registry of the Euro Heart Survey Programme to document patient characteristics, PCI details and hospital complications in different PCI indications. We examined the impact of TIMI-3 flow after PCI of the culprit lesion in patients with STEMI and NSTE-ACS in clinical practice.
Results: TIMI 3 flow was reached in 90.5% of patients undergoing primary PCI for STEMI and in 95.3% of patients undergoing PCI for NSTE-ACS. STEMI patients with TIMI-3 flow were younger, less often had prior MI or prior CABG. No relevant differences were found in the localization of the culprit stenosis, but less patients with TIMI-3 after PCI had TIMI-0 before PCI. Hospital mortality was lower in patients in whom TIMI 3 flow was achieved for both STEMI and NSTE-ACS.
Conclusion: TIMI-3 flow was not achieved in 9.5% of patients undergoing primary PCI for STEMI and in 4.7% of patients undergoing PCI for NSTE-ACS. Achievement of TIMI-3 was associated with significantly lower hospital mortality for both STEMI as well as NSTE-ACS in clinical practice.
- Acute coronary syndromes
- Myocardial infarction, STEMI
- Myocardial infarction, NSTEMI
- Percutaneous coronary intervention
- © 2013 by American Heart Association, Inc.