Abstract 14519: Relation Between Myocardial Edema and Left Ventricular Wall Motion Recovery in Patients With Takotsubo Cardiomyopathy
Background: Takotsubo cardiomyopathy is characterized by transient reversible systolic dysfunction of the apical and/or mid segments of the left ventricle (LV). However, there is little information about recovery process of LV systolic dysfunction in patients with takotsubo cardiomyopathy.
Methods: Between June 2007 and October 2012, 27 patients with takotsubo cardiomyopathy underwent cardiovascular magnetic resonance imaging (CMR) within 3 days after the onset to evaluate acute phase histological change of the diseased myocardium. The patients were classified into 2 groups according to the complete recovery of regional LV wall motion >7 days (n=24) and ≤7 days (n=16). Regional myocardial edema was defined as high intensity in T2-weighted images of CMR.
Results: There were no significant differences between the 2 groups in terms of clinical characteristics, ECG parameters, and LV ejection fraction. Regional myocardial edema was observed more frequently in the late recovery group compared to the early recovery group (100% vs. 56%, p<0.05).
Conclusion: Acute phase myocardial edema may be associated with recovery process of LV wall motion abnormality in patients with takotsubo cardiomyopathy.
- © 2013 by American Heart Association, Inc.