Abstract 13977: Characteristics and Outcomes of Young Patients, = 45 Years, Undergoing Percutaneous Coronary Intervention During Bare Metal Stent Era and Drug Eluting Stent Era
Background: Limited data is available about characteristics and outcomes of young patients, ≤ 45 years, undergoing percutaneous coronary intervention (PCI) during last two decades.
Methods: A total of 1640 patients, who were ≤ 45 years of age and underwent PCI during last two decades (1994-2012), was identified from the institution database. The patients were divided between two groups based on time period. 1994-2002, when Bare Metal Stent (BMS) was into use (BMS Era) and 2003-2012, when drug eluting stent (DES) was increasingly used (DES Era).
Results: Baseline and angiographic characteristics (Table 1) as well as long and short term outcomes (Table 2) were compared between the two groups. Kaplan Meier estimates indicated that 8 years survival was 92.2% in BMS era and 90.0% in DES era, which was not found to be significantly different between the two groups. More females patients, underwent PCI in DES era as compared to BMS era (26.8% vs. 19.6%, P-value 0.001), had higher 30 days mortality (1.6% vs. 0.2%, P-value 0.006) and more post procedural MI (3.5% vs. 1.7%, P-value 0.039) compared to males. Also, diabetics had worse long term mortality (19.4% vs. 9.3%, P-value <0.001) as compared to non-diabetics in the overall young patients cohort.
Conclusion: Patients who underwent PCI in the later decade (DES Era), presented with worse baseline and angiographic characteristics but had similar outcomes compared to patients who present in earlier decade (BMS Era). Young diabetics and female patients seem to have a higher risk of long term and 30-days mortality, respectively, as compared to non-diabetics and male patients.
- Percutaneous coronary intervention
- Transitions of care
- Coronary heart disease
- Risk factors
- Quality of medical care
- © 2013 by American Heart Association, Inc.