Abstract 13299: Impact of Female Gender on 5-Year-Mortality in Patients With Stable Coronary Artery Disease in Clinical Practice: Results of the STAR-Registry
Background: Gender differences in treatment and outcome of patients with coronary artery disease especially with acute coronary syndromes have been well described. Little is known about the impact of gender on long-term outcome of patients with stable coronary artery disease (CAD) in clinical practice.
Methods: Between Sept 2001 and March 2003, a total of 2,002 consecutive patients with angina pectoris and first angiographic diagnosis of CAD were enrolled in the STAR-Registry (50 centres). We examined the impact of gender on 5-year-mortality of stable CAD in clinical practice in Germany.
Results: Of 2002 patients with stable CAD, 600 patients (30.0%) were female, 1402 male (70.0%). Female patients were at mean 5 years older and more often had known diabetes. No significant differences were observed in other co-morbidities. Female patients less often had multi-vessel disease and impaired left ventricular function as compared to male patients. Female patients were more likely to undergo repeated subsequent PCI during the 5-year follow-up, and less likely to be referred to CABG. In univariate analysis female patients had similar 5-year mortality as compared to male patients. However, after correction for the differences in age, the prevalence of diabetes, impaired LV-function as well as for the rate of revascularisation therapy, female gender was associated with lower 5-year mortality in stable CAD in clinical practice (OR 0.75, 0.57-1.00).
Conclusion: Female gender was associated with a 25% lower 5-year mortality rate in patients with stable coronary artery disease in clinical practice.
- © 2013 by American Heart Association, Inc.