Abstract 13013: Prevalence and Distribution of Coronary, Thoracic Aorta and Cardiac Valve Calcifications on Routine Chest CT by Age and Gender
Background: Coronary artery calcifications (CAC), thoracic aorta calcifications (TAC) and valvular calcifications are valuable in the prediction of cardiovascular events. Normal values for routine chest CT as obtained in a common clinical radiological practice are non-existent. Structured reporting of calcifications by a simple visual grading score and defining age and gender specific cut-off values can provide CT readers an easy tool to identify subjects with a relative high-risk.
Methods: The study cohort comprised 1203 subjects (median age 60 years, 58% male), who underwent diagnostic chest CT for non-cardiovascular indications. CAC, TAC and valvular calcifications were graded using a well-validated ordinal score.
Results: The prevalence of CAC, TAC and valvular calcifications increased with age in both genders. The overall CAC prevalence was 74% in men and 68% in women. Males had a higher prevalence of CAC than females across all age categories, resulting in consistent higher quartile scores. The overall prevalence of TAC (51%) and valvular calcifications (31%) was equal for both sexes. For thoracic and valvular calcifications neither men nor women showed consistently higher rates of calcifications across all age categories. Hence, the quartile scores for TAC and valvular calcifications were also not consistently higher for men or for women across all age groups.
A set of curves showing the 75th percentile upper cut point of total CAC, TAC and cardiac valve scores are provided, as CAC scores quantified by the Agatston score ≥75th percentiles are associated with an increased risk of CHD.
Conclusions: The presented age- and gender specific quartile values of CAC, TAC and cardiac valve calcifications can provide guidance to CT readers in classifying subjects who have relative high calcifications scores. Referring these patients for timely preventive cardiovascular risk management may effectuate further decline of the global cardiovascular disease burden.
- © 2013 by American Heart Association, Inc.