Abstract 12986: The Neutrophil/lymphocyte Ratio is a Factor for Predicting Concomitant Coronary Artery Disease in Patients with Abdominal Aortic Aneurysms
Background: Abdominal aortic aneurysm is a progressive atherosclerotic condition, and it is not unusual to find such aneurysms accompanied by coronary artery disease (CAD). CAD is considered a serious risk factor that impacts the prognosis in abdominal aortic aneurysm surgical cases. However, no risk factors that allow the prediction of accompanying CAD among abdominal aortic aneurysm patients have yet been identified. Recent reports suggest that the neutrophil/lymphocyte ratio (NLR) can be a factor for predicting the severity and prognosis in patients with CAD. This study looked at abdominal aortic aneurysm cases and considered whether NLR may be a predictive factor in the concomitant presence of CAD.
Method: The study focused on 81 patients awaiting surgery for abdominal aortic aneurysms, who underwent coronary angiography examinations for the purpose of undergoing the detailed examination of the coronary artery. NLR and a range of other blood sampling markers were measured, and the patients were divided into groups according to the concomitant presence of CAD.
Results: Forty-two cases (52%) tested positive for CAD. The NLR of the CAD group was compared with that of the non-CAD group, and found to be significantly higher (2.48±1.02 vs. 1.91±0.73 p≤0.01). NLR rose significantly in line with an increase in the number of coronary lesions. According to a multivariable analysis, NLR was an independent risk factor for concomitant CAD.
Conclusion: These results suggest that measuring the NLR may be an effective method for stratifying the risk of concomitant CAD among patients with abdominal aortic aneurysms.
- © 2013 by American Heart Association, Inc.