Abstract 12743: Prolonged Duration of Myocardial Early Systolic Lengthening Predicts Late Coronary Restenosis and New Coronary Lesion after Coronary Intervention
Introduction: Recent study suggested that ischemic myocardium with reduced active force will lengthen when left ventricular (LV) pressure rises during early systole before onset of systolic shortening.
Hypothesis: We hypothesized that the duration of LV early systolic lengthening (ESL) could identify myocardial segments associated with restenosis or new coronary lesion 9 months after coronary intervention.
Methods: We retrospectively examined prospectively collected data from consecutive 107 patients with coronary artery stenosis for revascularization. Speckle tracking echocardiography was performed bofore coronary angiography and at follow-up scheduled after 9 months after revascularization.
Results: We identified 857 segments before and 9 months after revascularization. The duration of ESL was significantly prolonged in segments associated with coronary stenosis (≥50%) compared with segments without coronary artery stenosis (46 ± 28 ms vs. 13 ± 26ms, P≤ 0.0001). Prolonged duration of ESL showed the accuracy in detecting coronary restenosis or new coronary lesion (≥50%) with an area under the receiver-operating characteristic curve of 0.81 with the best cut-off value of 11.5ms.
Conclusions: Duration of myocardial ESL was prolonged in segments associated with restenosis and new coronary lesion. This might be a useful parameter to predict coronary lesion before follow-up coronary angiography.
- © 2013 by American Heart Association, Inc.