Abstract 12691: Post Procedural Skin Perfusion Pressure Predicts One-year Clinical Outcomes after Endovascular Therapy for Patients with Critical Limb Ischemia
Background: Although skin perfusion pressure (SPP) predicts wound healing of ischemic ulcer in patients with critical limb ischemia (CLI), correlation between clinical outcomes of CLI patients and SPP after endovascular therapy (EVT) has not been systematically studied.
Methods: This study was a sub-analysis of OLIVE registry (UMIN000002830) for assessing the reliability of SPP on clinical outcomes. Consecutive 274 CLI patients complicating with tissue loss due to infrainguinal arterial lesions who underwent EVT were enrolled. Binomial logistic regression analysis was performed with amputation free survival (AFS, death or major amputation), modified-MALE (major amputation or any reintervention) and wound healing as dependent variables and post procedural SPP (mean of dorsal and plantar value) as an independent variable.
Results: The average of pre and post procedural SPP was 28±11 mmHg and 46±18 mmHg, respectively. After binomial logistic regression analysis, the post procedural SPP was correlated with one year AFS, modified-MALE and wound healing. (Figure)
Conclusion: The post procedural SPP can predict clinical outcomes after EVT for patients with CLI.
- © 2013 by American Heart Association, Inc.