Abstract 12452: Significant Impact of Self-reported Eating Speed on the Prevalence of Metabolic Syndrome and Plasma Adiponectin Level
Objective: Metabolic syndrome (MetS) is an established risk factor for cardiovascular disease and adiponection has an important role in the pathogenesis of MetS. Little is known about the associations of eating speed on MetS and adiponectinalthough the correction of fast eating is one of practical and effective therapies for obese subjects. Therefore, the aim of this study was to examine the hypothesis that eating speed has an impact on the prevalence of MetS and the secretion of adiponectin.
Methods: We divided a total of 840 Japanese male workers (40-65 years of age) into three groups according to self-reported eating speed: slow (n=60), medium (n=525) and fast (n=255). All subjects were measured plasma levels of total adiponectin. MetS was defined according to the criteria proposed by six major world organizations including the International Diabetes Federation.
Results: Of the MetS components, the frequency of elevated waist circumference significantly increased with increases in eating speed (slow: 13.3%, medium: 37.9%, fast: 51.8%, p≤0.05). The prevalence of MetS was positively associated with increases in eating speed (slow: 3.3%, medium: 13.7%, fast: 17.7%, p≤0.05). The multivariate-adjusted odd ratio for the presence of MetS compared with subjects with self-reported medium eating was 0.25 (95% confidence interval: 0.04-0.80, p≤0.05) for those with slow eating and 1.63 (1.06-2.48, p≤0.05) for those with fast eating. According to receiver operating characteristic curve analysis, the cutoff level of adiponectin for predicting MetS was 4.07 μg/ml (sensitivity: 76.1%, specificity: 49.7%). Compared with subjects with medium eating, the multivariate-adjusted odd ratio for the presence of hypoadiponectinemia defined as adiponectin ≤4.07 μg/ml was 0.52 (0.29-0.93, p≤0.05) for those with slow eating and 0.92 (0.67-1.26) for those with fast eating.
Conclusions: In middle-aged men, we demonstrated the significant impact of self-reported eating speed on the prevalence of MetS and the association between slow eating and the reduced frequency of hypoadiponectinemia. These results indicate that we should give careful consideration to the correction of eating speed in the prevention and therapy for MetS and cardiovascular disease.
- © 2013 by American Heart Association, Inc.