Abstract 12444: Vasa Vasorum Neovascularization Predicts Peri-procedural Myocardial Injury During Coronary Stenting: An Intravascular Ultrasound Study
Background: Previous studies have suggested that vasa vasorum (VV) neovascularization is related to coronary plaque vulnerability. Vulnerable plaque may have higher risk for peri-procedural myocardial injury during coronary stenting.
Purpose: The purpose of this study was to assess impact of VV on peri-procedural myocardial injury as assessed by cardiac troponin T (cTn-T) elevation after coronary stenting.
Methods: A total of 40 stable angina patients were enrolled and studied. IVUS pullback imaging was performed before intervention. VV was defined as a small (≤1mm) tubular or vesicular, low-echoic structures observed exterior to media. Within 24h after coronary stenting, cTn-T level was measured. We assess the relationship between maximal number of the VV and cTn-T elevation after PCI.
Results: Twenty-three of 40 patients (58%) showed cTn-T elevation after coronary stenting (0.009±0.002 to 0.219±0.279 ng/ml). CTn-T elevation showed significantly higher maximal number of the VV in the culprit lesions than those without cTn-T elevation (2.5±1.2 vs. 1.7±0.7, p=0.011).
Conclusions: VV may predict peri-procedural myocardial injury during coronary stenting.
- © 2013 by American Heart Association, Inc.