Abstract 11118: Temporal Trends in Clinical Characteristics of Patients Without Known Coronary Artery Disease Presenting With a First Episode of Myocardial Infarction
Background: Recent public health initiatives have increased the focus on primary preventive measures with the intent of delaying/preventing a first event in individuals without known coronary artery disease (CAD). The aim of this study was to evaluate the change in risk factor profile over time of patients without known CAD presenting with a first episode of myocardial infarction.
Methods: In the American Heart Association’s Get With The Guidelines-CAD national registry, 100,884 patients without known CAD presenting with an acute myocardial infarction from 408 hospitals were evaluated between 2002 and 2008. The time trend of the proportion of patients with >3 of 6 traditional cardiovascular risk factors (age >45 years for men or >55 years for women, male sex, diabetes mellitus, hypertension, hyperlipidemia, tobacco use) was analyzed. This analysis was repeated for the presence of >2 of 4 modifiable cardiovascular risk factors and each individual risk factor. Analyses were stratified by presentation of non-ST-segment elevation myocardial infarction (NSTEMI) versus STEMI.
Results: The proportions of patients with >3 traditional risk factors and >2 modifiable risk factors have slightly decreased over time in the NSTEMI and STEMI cohorts (Figure). After adjusting for age and gender, the time trend of proportion of patients (odds ratio/1 year) with modifiable risk factors for both the NSTEMI and STEMI cohorts are shown in the Table.
Conclusions: While the risk factor profiles in patients presenting with first NSTEMI and STEMI have shown slight improvements over time, the changes are modest with no single risk factor exceeding a prevalence change of 5%.
- © 2013 by American Heart Association, Inc.