Abstract 10747: Gender Differences in the Incidence, Management and Outcomes of In-Hospital Cardiac Arrest Complicating Acute Coronary Syndromes: A 20-Year Experience From a Middle-Eastern Country (1991-2010)
Objectives: There is scarce data about gender differences in in-hospital cardiac arrest (IHCA) complicating acute coronary syndromes (ACS), particularly from the developing countries. In the current study we examined gender differences in the incidence, risk profiles, management and outcome of IHCA in the setting of ACS hospitalization using a 20-year national registry from a Middle-Eastern Country.
Methods: Retrospective analysis of all patients hospitalized with ACS that developed IHCA in Qatar from 1991 through 2010 was made. Patients were divided into two groups according to gender. Clinical characteristics, management and outcomes were analyzed.
Results: During the 20-years period 16736 patients were hospitalized with ACS in Qatar from 1991 to end of 2010; 2474 women and 14262 men. Of these 840 patients developed IHCA during hospitalization; 205 women and 635 men with an incidence rate of 8.3% and 4.4%, respectively; p= 0.001. Women with IHCA were 8 years older and had a significantly higher prevalence of hypertension and diabetes mellitus, while current smoking status was significantly more common in men with IHCA. Women with IHCA were significantly less likely to receive thrombolysis and coronary procedures compared to men. The in-hospital mortality rate was significantly higher in women with IHCA compared to men (85.9% versus 78.9%; p=03) [table].
Conclusions: Our study demonstrates that women in our region have a higher incidence of IHCA in the setting of ACS hospitalization compared to men. These women were significantly undertreated with revascularization therapies and had a lower in-hospital survival rate compared to men. The current study underscores the need to study gender differences among other ethnicities around the world.
- © 2013 by American Heart Association, Inc.