Abstract 10299: Influence of Diabetes Mellitus on the Presentation Symptoms and In-hospital Outcomes of Patients With Atrial Fibrillation: From a 20-year Registry
Objectives: The aim of this study was to identify whether patients with Diabetes Mellitus (DM) have different presentation symptoms and in-hospital outcome compared to non-diabetic patients when presenting with atrial fibrillation (AF) in a real-world population.
Methods: Retrospective analysis of all patients hospitalized with AF in Qatar from 1991 through 2010 was made. Patients were divided into two groups according to the presence or absence of DM on presentation. Clinical characteristics, symptoms of presentation and outcome were analyzed.
Results: During the 20-years period, 3850 patients were hospitalized for AF; 1157 (30.1%) had DM on presentation while 2693 (69.9%) had no DM. DM patients were 10 years older, had more prevalence of hypertension, underlying coronary artery disease, dyslipidemia and chronic kidney disease (all, P value =0.001). Patients with DM were significantly less likely to present with palpitations compared to non-DM patients (35.3% versus 48.9%; P value =0.001). Shortness of breath and chest pain were significantly more common in patients with DM compared to non-DM patients [table]. The in-hospital mortality rate was significantly higher in patients with DM (6.6% versus 3.1%; P value =0.001).
Conclusions: Our study demonstrates that DM significantly affects the presentation symptoms as well as the in-hospital survival of patients with AF. Further research is warranted to confirm and explain our observations.
- © 2013 by American Heart Association, Inc.