Abstract 10068: Quantification of Shunt Flow through Ventricular Septal Defect With a 3D Echocardiographic Doppler Flow Program: An in Vitro Study
Background: Quantification of shunt flow through a ventricular septal defect (VSD) is crucial but difficult with conventional 2D methods. Our study tested a new 3D Doppler method to evaluate flow through a modeled VSD in a controlled phantom study.
Methods: Five freshly harvested porcine hearts were studied. A balloon was inserted into each ventricle and fixed at the mitral annulus or tricuspid annulus. A VSD was modeled by a plastic tube with five different sizes (11- 25mm) connecting the right and left ventricles (RV, LV). Each heart was passively pumped at stoke volumes (SV) 30-70ml using a calibrated pump at increments of 10ml. 3D flow volumes were obtained at RV and LV sides using the Siemens Acuson SC2000 scanner and its 4Z1c 2.8MHz transducer (Siemens Medical Solutions) with color frame rates (CFRs) at 15,20 and 27 volumes/second (vps). Flow volumes were analyzed offline for shunt flow though the VSD at each SV at RV and LV sides, using prototype software.
Results: Linear regression analyses demonstrated superior correlation between calculated volume and pump-SV in right side (all R2>0.93) than left side (all R2>0.76) in three CFR levels. There were no significant differences among different CFRs.
Conclusion: This novel 3D flow method could accurately evaluate VSD shunt flow at both side regardless of angle and flow direction, right side flow is easier to assess and more accurate.
- © 2013 by American Heart Association, Inc.