Abstract P437: Diversity in Hispanic Background and Burden of Metabolic Syndrome Abnormalities: A Report from the HCHS/SOL
Background: More than one-third of the 2003-06 adult U.S. population has the metabolic syndrome (MS). Its prevalence is the highest among Hispanic adults, but the distribution of the MS by Hispanic background, and particularly of the MS components that are modifiable by life style factors are unknown.
Methods: We examined MS prevalence among 16,319 adults (52% women in the study population) ages 18-74 years enrolled (2007-2010) in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) who were assessed for the MS. A two-stage area probability sample of households was used to enroll Hispanics who self-identified as Cuban, Puerto Rican, Mexican, Dominican, and Central/South American. The MS was defined according to the AHA/NHLBI definition. All results were adjusted to the study design and to the 2010 U.S. standard population by sex, age and Hispanic background.
Results: The overall prevalence of the MS was 35% (36% among women; 34% among men), comparable to reports by NHANES based on probability sample of mostly Mexican-Americans. Marked differences in the prevalence of the MS were seen by age, body mass and Hispanic background. The prevalence of the MS among those 18-44, 45-64 and 65-74 years old was 23%, 50% and 62% among women; and 25%, 42% and 55% among men. Frequency of the MS increased with BMI classified as normal weight (BMI >25), overweight (BMI 25-29.9) and obese (BMI 30+). Among women, MS prevalence was 12% among normal weight, 31% among overweight and 51% among obese. Among men, MS prevalence was 8% among normal weight, 25% among overweight and 57% among obese. The prevalence of the MS by Hispanic background ranged from 27% among South American women to 41% among Puerto Rican women. For men prevalence estimates ranged from 26% among South Americans to 35% among Cubans. The profile of MS components differed by sex. Abdominal obesity was present in 93% of the women who had the requisite minimum of 3 traits for the MS compared to 62% of men. More men (70%) than women (50%) who met the minimum criterion for the MS had elevated fasting plasma glucose.
Conclusion: Our findings from the HCHS/SOL study indicate that the prevalence of the MS varies according to sex, age, adiposity and Hispanic background. Women and men of diverse Hispanic/Latino backgrounds exhibit a high burden of metabolic abnormalities associated with insulin resistance. These groups are thus at high predicted life time risk of diabetes and its cardiovascular sequelae.
- © 2013 by American Heart Association, Inc.