Abstract P302: The Sex and Race Specific Relationship Between Anthropometry and Body Composition by Computed Tomography: The Multi-Ethnic Study of Atherosclerosis
Introduction Evidence suggests that visceral fat plays a larger role in cardiometabolic disorders than adipose tissue stored in other depots. Few studies have investigated the relationship of the most commonly used anthropometric measurements with underlying body composition or have determined if these relationships differ by sex and race.
Aim and Hypothesis We determined the best fitting cross-sectional relationship between common anthropometric indices and adipose tissue area from different anatomic compartments and tested the hypothesis that these differed by sex and race.
Methods After exclusions for relevant conditions and uncodable CT scans, 1373 individuals in the Multi-Ethnic Study of Atherosclerosis who underwent CT scans of the abdomen were assessed for visceral fat, subcutaneous fat, and lean muscle areas by semi-automated segmentation of the body compartments. Participants were 49% (673 of 1373) female with a mean age of 62 years at enrollment. Regression models were used to determine the magnitude and significance of the associations between anthropometric measures and body composition by sex and race.
Results The relationships of anthropometric indices with visceral fat were heterogeneous by sex, with a steeper slope for men than for women. Interaction by race was less consistent across anthropometric indices, with the exception that African American race was associated with a lower slope for visceral fat. Anthropometric indices were positively associated with subcutaneous fat, but there were few interactions by sex or race. Anthropometry was weakly associated with lean mass.
Conclusion These data suggest that the relationship between anthropometry and visceral fat may differ by sex and that the relationship between anthropometry and lean mass is weak, indicating that differences in anthropometry are primarily due to differences in adiposity. When body mass index or waist circumference is used as a proxy for visceral fat, researchers should consider using separate models by sex and race.
Table 1. Slope estimates for CT derived body composition by anthropometric indices in MESA
- © 2013 by American Heart Association, Inc.