Abstract P300: Ideal Cardiovascular Health and Abdominal Obesity in a Biracial Sample of Children
Background: Ideal Cardiovascular (CV) Health is an AHA 2020 Impact Goal but the degree to which it is related to adiposity in specific body depots is unknown. The aim was to investigate how Ideal CV Health relates to abdominal visceral (VAT) and subcutaneous (SAT) adipose tissue and total body fat (TBF) with and without including BMI as a criterion.
Methods: The sample consisted of 363 white and African American (AA) children (5-18 y). Ideal Health criteria were: non-smoking, physical activity (PA) of 60 min, recommended diet, BMI <85th percentile, total cholesterol < 170 mg/dL, blood pressure <90th percentile and fasting glucose < 100 mg/dL. Abdominal VAT and SAT were measured by MRI and TBF was assessed by DXA. VAT, SAT and TBF were regressed against age and the sex- and race-specific residuals were divided into quartiles to represent age-adjusted adiposity. The highest quartile represented the “at-risk” group. Logistic regression, controlling for age and race, was used to calculate odds ratios which were converted to relative risks as per Zhang et al (JAMA 1998; 280; 1690-91).
Results: A total of 24.2% (88/363) of the sample had ≤ 3, 36.4% (132/363) had 4, and 39.4% (143/363) had ≥ 5 Ideal Health criteria. Possession of the Ideal criteria was: 99% non-smoking, 9% PA, 2% diet, 53% BMI, 63% cholesterol, 93% BP and 96% glucose. White participants possessed more criteria (χ2=17.7; p=0.001) than AAs but there were no sex differences (χ2 =1.0; p= 0.91). Those with fewer Ideal Health criteria had a significantly greater risk of having high abdominal VAT, SAT and TBF (Table). Once BMI was removed as a criterion due to its high correlation with adiposity, the RR estimates were substantially reduced.
Conclusion: These data lend support to the AHA Ideal CV Health criteria and that an increased number of criteria are related to lower abdominal and total adiposity. It appears that a large part of the association can be explained by BMI.
Table. Relative risks (RR) for the prediction of the upper quartile of adiposity measures from the number of Ideal Health criteria
- © 2013 by American Heart Association, Inc.