Abstract P230: Sex Disparities in Acute Myocardial Infarction Incidence: Do Migrants Differ from the Host Population?
Background Worldwide the incidence of acute myocardial infarction (AMI) in men exceeds that in women, particularly in the young. As the extent of sex disparities varies widely between countries, it is plausible that variations exist between migrants and the host population. We assessed whether there are differences in sex disparity in AMI incidence between migrants and ethnic Dutch, and whether the magnitude of these differences change with age.
Methods A nationwide register based cohort study was conducted (n=7,601,785) between January 1st 1997 and December 31st 2007. Cox Proportional Hazard Models were used to estimate the sex disparity in AMI incidence in migrant groups and ethnic Dutch stratified by age (30-54, 55-64, ≥65).
Results Among ethnic Dutch, AMI incidence was higher in men than in women (Hazard Ratio (HR): 2.23; 95% Confidence Interval (95% CI): 2.21-2.25). Among migrants from the immediate surrounding countries (Belgium, Germany) similar sex disparities were found, whereas sex disparities were greater in the majority of other migrant groups under study. Most pronounced results were found among migrants from Turkey (HR: 3.98; 95% CI: 3.51-4.51), and South Asia (HR: 3.92; 95% CI: 2.45-6.26). Sex disparities were predominantly evident in those below 55 years of age, and were mainly caused by a higher AMI incidence in migrant men compared to ethnic Dutch men.
Conclusion Health prevention strategies should focus on a reduction of AMI incidence in young migrant men, especially those originating from Turkey and South Asia. Furthermore, an increase in AMI incidence in their female counterparts should be prevented.
- © 2013 by American Heart Association, Inc.