Abstract P174: Long-Term Effect of Multidisciplinary Lifestyle Intervention on Adiposity and Cardiometabolic Health in Adolescents with Obesity
Background: The prevalence of obesity has increased dramatically among children and adolescents. Consequence of the rising prevalence of obesity is an earlier appearance of metabolic syndrome and type 2 diabetes. In this regard, health care professionals are confronted to the challenge of properly treating this condition. There is also a need for documenting the long-term effect of multidisciplinary lifestyle interventions on cardiometabolic risk factors.
Objective: The objective of the present study was to examine the long-term effects of a 16-week lifestyle modification program on adiposity and metabolic risk factors in obese adolescents.
Design/Methods: Thirty-three obese adolescents (19 boys and 14 girls) from 11 to 16 years of age (14.0 ± 1.6 years) were selected to participate in this study. The aim of the intervention was to improve nutritional and physical activity habits. Each subject was followed by a multidisciplinary team at the Adolescent medicine clinic and trained three sessions per week for 16 weeks. The exercise program focused on endurance type activities and all training sessions were supervised and performed in groups. Physical and metabolic variables were measured at baseline, at mid-time and at the end of the intervention as well as 4 months and 8 months follow-up.
Results: Body mass index (33.6 to 32.7 kg/m2, p=0.0002) and waist circumference (102.4 to 100.5 cm, p=0.05) were significantly reduced after the 16-week intervention program. We also found a significant decrease in triglyceride concentrations (1.35 to 1.07 mmol/l, p=0.05) as well as in total cholesterol/HDL cholesterol ratio (4.43 to 3.94, p<0.0001) whereas HDL cholesterol levels were increased (1.02 to 1.14 mmol/l, p=0.003). The number of participants characterized by at least 2 of 7 risk factors (total cholesterol, LDL cholesterol, apolipoprotein B, HDL cholesterol, triglycerides, insulin and glucose) was also decreased. Therefore, no significant change was found in maximal oxygen uptake after the intervention. We were also interested to evaluate the long-term effect of multidisciplinary lifestyle intervention on cardiometabolic risk factors. We found that anthropometric and metabolic variables were returned to baseline levels only 4 months after the 16-week intervention program.
Conclusions: These results indicate that a multidisciplinary intervention which include exercise training may significantly improve cardiometabolic risk profile in obese adolescents. However, the multidisciplinary lifestyle intervention proposed had limited long-term effects on anthropometric and metabolic parameters. Longitudinal studies will be needed to explore how intervention programs for childhood obesity should be improved.
- © 2013 by American Heart Association, Inc.