Abstract P113: Combined Effects of Lifestyle Factors on Chronic Disease Mortality in Men and Women
Background: The impact of lifestyle factors on chronic disease mortality in the U.S. population remains less explored. We investigated the combined effects of healthy lifestyle behaviors (never smoking, physically active, and healthy diet) on chronic disease mortality in US men and women.
Methods: We followed up 15,801 men and women, aged 20 to 89 years, who participated in the Third National Health and Nutrition Examination Survey. All participants completed baseline lifestyle behavior questionnaires. A healthy lifestyle profile was defined as never smoking, physically active, and a healthy diet defined by the American Heart Association Strategic Committee (Lloyd-Jones, et al., 2010). There were a total of 2393 chronic disease deaths (306 CVD, 653 cancer, 292 respiratory disease, 195 diabetes mellitus) during an average of 13.7 years of follow-up (216,877 person years).
Results: After adjustment for age, sex, race, and other multiple risk factors, there was an inverse association between a great number of healthy lifestyle behaviors and chronic disease mortality (P-value for trend <0.001). Men and women who were never smoked, physically active, and had a healthy diet had a 45% lower risk of chronic disease mortality (95% CI: 34% to 55%) compared with those men and women with no healthy lifestyle behaviors. Persons with all 3 healthy lifestyle behaviors had a 6.7 year (95% CI: 4.7 to 8.5) longer life expectancy from chronic disease mortality compared with persons with no healthy lifestyle behaviors. Approximately 33% (95% CI: 20% to 44%) of chronic disease deaths might have been avoided if men and women had maintained all 3 healthy lifestyle behaviors.
Conclusions: Being physically active, never smoking, and having a healthy diet is associated with lower risk of chronic disease mortality in US men and women.
- © 2013 by American Heart Association, Inc.