Abstract P108: Associations between Anthropometric Indices and the Prevalence of Heart Disease in Iran: The Golestan Cohort Study
Background: Both high and low body mass index (BMI) are associated with heart disease (HD). However, data are relatively lacking regarding the relationship between life-course trends in BMI and HD in low- and middle-income countries (LMICs).
Objective: To investigate the relationship between prevalent HD and anthropomorphic indices such as BMI, waist circumference (WC) and waist to hip ratio (WHR), as well as body size perception from adolescence to adulthood.
Methods: Baseline data from the Golestan Cohort Study, a prospective population-based study in Iran, were used in this cross-sectional analysis. Current anthropometric indices were measured and body size perception using standard pictograms was assessed for age 15, age 30, and at the time of interview. We used logistic regression to evaluate associations of prevalent HD with anthropometric indices. Statistical analyses were performed using STATA version 11.
Results: Complete data were available for 50,044 participants (age 40-75 years), of whom 6.1% reported a history of HD. For men and women, current BMI, WC, and WHR were associated with prevalent HD (p<0.001). Prevalence of HD increased with each quintile of WC and WHR (e.g. adjusted OR (95% CI) for highest WC quintile for men (≥105 cm) and women (≥108 cm) was 1.56 (1.28, 1.91) and 1.47 (1.24, 1.73), respectively). Among men, there was a U-shaped relationship between HD and body size perception at younger ages. Men also had a U-shaped relationship between HD and changes in body size perception over time, while women had a U-shaped relationship between HD and changes in body size perception from adolescence to early adulthood, but demonstrated a J-shaped pattern from early to late adulthood (Figure).
Conclusion: Prevalent HD was associated with current anthropometric indices and temporal changes in body size perception for men and women. Public health interventions focused on the cumulative lifetime burden of risk factors such as obesity on cardiovascular morbidity and mortality are essential, particularly in LMICs.
- © 2013 by American Heart Association, Inc.