Abstract MP83: Effects of Sleep Duration and Insomnia Status on Prevalence of Coronary Heart Disease in Older Adults -- The Chicago Healthy Aging Study (CHAS)
Effects of Sleep Duration and Insomnia Status on Prevalence of Coronary Heart Disease (CHD) in Older Adults -- The Chicago Healthy Aging Study (CHAS).
Background: Previous studies have documented that short sleep duration is associated with an increased risk of coronary heart disease (CHD) mortality and morbidity. However, only a few population-based studies have information on the association of short sleep duration and CHD risk taking into account the role of sleep disturbance in older populations.
Methods: Using data from the Chicago Healthy Aging study (CHAS), we investigated a cross-sectional association of a combination of short sleep duration (≤ 6 hours) and insomnia status (either cannot get to sleep within 30 minutes or waking up in the middle of the night or early morning three or more times per week) assessed by the Pittsburgh Sleep Quality Index (PSQI) and the prevalence of CHD events assessed by a self-reported questionnaire and from ECG results (see Table and Table Footnote for definitions of sleep categories and CHD).
Results: The study sample consists of 950 men and 356 women, ages 65-84 (mean age 71) in 2007-10; 9% were African American. The proportion of participants who had CHD was highest (26%) among those who reported to have shorter duration of sleep and had insomnia, and lowest (18%) among those without both short sleep duration and insomnia (p-value = 0.044). Although there was no evidence for an interaction between sleep duration and insomnia in affecting prevalence of CHD (P-value for the interaction term =0.617), they were associated with CHD. Compared to the group with shorter sleep duration and insomnia, adjusted odds (95% confidence interval) of having CHD in all other groups were lower, with the lowest [0.57 (0.39-0.82)] in those with > 6 hours of sleep and without sleep problems (see Table).
Conclusion: In older age, shorter sleep duration and insomnia were associated with the greatest likelihood of having coronary heart diseases. These results suggest that sleep duration may be an important marker for CVD.
- © 2013 by American Heart Association, Inc.