In the article by Rho et al, “Important Differences in Mode of Death Between Men and Women With Heart Failure Who Would Qualify for a Primary Prevention Implantable Cardioverter-Defibrillator,” which was published in the November 13, 2012 issue of the journal (Circulation. 2012;126:2402–2407), an error occurred. The sudden death variable used by the authors in one of the 5 trials used in the manuscript was not “sudden death”, but was rather “sudden death without worsening heart failure death.” This error led to a lower overall sudden death rate as well as a higher other death rate (defined as not sudden or pump failure death) than would have been found had the relevant variable from one trial not been miscoded.
Despite this error, with its correction, there are no meaningful differences in either the lower proportion of sudden death in women vs. men (32% new vs. 31% original) or in the conclusions of the manuscript.
The major finding that has changed is that the proportion of sudden death overall has increased overall (48.4% current vs. 39.9% original), and in both women and men (Table 2 and Figure 2). Also, the hazard ratios in the Fine and Gray model are changed minimally (Table 3). Finally, Figure 3 has a lower proportion of other deaths; though this was not the focus of the manuscript.
The authors have supplied the corrected values for Table 2 & 3 and Figure 1 (sudden death). Also, though the findings in Figure 3 were not a focus of the manuscript, they have also supplied a corrected Figure 3 (other death).
Percentages, hazard ratios, and confidence intervals have been updated throughout the abstract, results, and discussion.
The corrections have been made in the current online version of the manuscript. The authors regret the errors.
- © 2013 American Heart Association, Inc.